Relationship between Physical Activity Level, Telomere Length, and Telomerase Activity
نویسندگان
چکیده
منابع مشابه
telomerase activity and telomere length in aml-m3 patients
introduction: the telomeric dna together with its associated proteins protects the chromosome ends from degradation or aberrant recombination. telomerase and telomere are closely associated with development of cancers. in this study we aim to investigate the significance of telomerase activity (ta) and telomere length (tl) in patients with acute promyelocytic leukemia (apl). methods: peripher...
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Telomeres, comprised of short repetitive sequences, are essential for genome stability and have been studied in relation to cellular senescence and aging. Telomerase, the enzyme that adds telomeric repeats to chromosome ends, is essential for maintaining the overall telomere length. A lack of telomerase activity in mammalian somatic cells results in progressive shortening of telomeres with each...
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Relationship Between Leukocyte Telomere Length, Telomerase Activity, andHippocampal Volume in Early Aging Leukocytetelomere length(TL)providesanindexofcellularage thatpredictstheincidenceofage-relateddiseasesandearlymortality inolderadults.1Telomeraseadds telomeric repeats to terminal DNA, a critical process that helps stall genomic instability and apoptotic events that are triggered when telom...
متن کاملThe effect of high intensity interval training on telomere length and telomerase activity in non-athlete young men
Introduction: Telomeres are DNA portions that are located on the two ends of the chromosome. Telomeres play an important role in cellular life. Exercise is one of the factors that contributes to their control. The purpose of the present study was to investigate the effect of 8 weeks of high intensity interval training (HIIT) on telomere length and telomerase activity in non-athletic young men. ...
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Human linear chromosomes are capped by specialized DNA-protein structures called telomeres. The present study analysed the telomerase activity, hTERT protein and telomere length in meningiomas and gliomas in relation to their WHO grading. Fifty-three freshly dissected tumour biopsies were analysed for telomerase activity, hTERT protein expression and telomere length. Telomerase activity was exa...
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ژورنال
عنوان ژورنال: Medicine & Science in Sports & Exercise
سال: 2008
ISSN: 0195-9131
DOI: 10.1249/mss.0b013e31817c92aa